Publications
Read our peer reviewed research here
-
“Transcriptional changes in the mammary gland during lactation revealed by single cell sequencing of cells from human milk” Twigger, A.J. Engelbrecht, L. K. Bach, K. Schultz-Pernice, I. Pensa, S. Stenning, J.P. Petricca, S. Scheel, C. H.* Khaled, W. T.* NatComms, 2022
“Human breast tissue dissociation induces compositional and transcriptional bias as detected by flow cytometry and single cell RNA sequencing” Twigger, A.J.* Engelbrecht, L. K.* Ganz, H. M. Gabka, C. Khaled, W. T. Scheel, C. H. bioRxiv, 2020
“Morphological analysis of human milk membrane enclosed structures reveals binucleated cells and cell-like milk fat globules” Schultz-Pernice, I. Meixner, L. K. Petricca, S. Scheel, C. H.* Twigger, A. J.* J Mammary Gland Biol Neoplasia, 2020
“Expression of granulisyn, perforin and granzymes in human milk over lactation and in the case of maternal infection” Twigger, A.J*., Küffer, G.K., Geddes*, D.T., Filgueria, L. Nutrients, 2018
“Gene expression in breastmilk cells is associated with maternal and infant characteristics” Twigger, A.J. Hepworth, A.R. Tat-Lai, C. Chetwynd, E. Stuebe, A. M. Blancafort, P. Hartmann, P.E. Geddes, D.T. Kakulas, F. Sci. Rep., 2015
“Breastmilk cell and fat contents respond similarly to removal of breastmilk by the infant” Hassiotou, F. Hepworth, A. R. Williams, T. M. Twigger, A. J. Perrella, S. Lai, C. T. Filgueira, L. Geddes, D. T. Hartmann, P. E. PloS one, 2013
“Breastmilk is a novel source of stem cells with multi-lineage differentiation potential” Hassiotou, F. Beltran, A. Chetwynd, E. Stuebe, A. Twigger, A. Metzger, P. Trengove, N. Tat Lai, C. Filguiera, L. Blancafort, P. & Hartmann, P. Stem Cells, 2012
-
“25 years of research in human lactation: from discovery to translation” Geddes D. T. Gridneva, Z. Perrella, S. L. Mitoulas, L. R. Kent, J.C. Stinson, L.F. Tat Lai, C. Sakalidis, V. Twigger, A. J. Hartmann, P. E. Nutrients, 2021
“Mammary gland development from a single cell ‘omics view” Twigger, A.J. Khaled, W. T. Semin. Cell Biol., 2021
“Advances in stem cells and regenerative medicine: single-cell dynamics, new models and translational perspectives” Twigger, A.J. Scheel, C. H. Development, 2017
“Cells in human milk-what do they tell us” Twigger, A.J. Hartmann, P.E. Australian Biochemist, 2017
“Pluripotency genes and their function in the normal and aberrant breast and brain” Seymour, T. Twigger, A.J. Kakulas, F. Int. J. Mol. Sci., 2015
“From breast milk to brains: The potential of stem cells in human milk” Twigger, A. Hodgetts, S. Filgueira, L. Hartmann, P. & Hassiotou, F. 2013, J HUM LACT
-
News articles
The Naked Scientists podcast interviewed by Julia Ravey Human Milk Podcast (Listen now)
2022 BBC Look East (research feature): “Could breastmilk hold the key to understanding cancer?” by Richard Westcott
2020 Guardian, The Observer, Science: “Should mother's milk be produced in the lab? written by Zoë Corbyn
Data and code access
Access the Shiny app for Twigger et al. 2022 data
Access the Github code for Twigger et al. 2022 paper
Access the raw data for Twigger et al. 2022 paper